About boceprevir
Hepatitis C virus protease inhibitor
Used for
- Used with peginterferon alfa and ribavirin to treat chronic hepatitis C genotype 1.
Usual adult dose
800 mg by mouth three times daily with food, alongside peginterferon alfa and ribavirin.
Common side effects
- Anemia
- Fatigue
- Nausea
- Taste changes
Important warnings
- Not used alone; treatment requires other hepatitis C medicines.
- Can cause serious anemia and neutropenia.
- Avoid in moderate or severe liver impairment.
- Do not use with certain medicines that interact strongly.
Pregnancy
Used with ribavirin, which can cause severe birth defects or pregnancy loss; pregnancy must be avoided during treatment and for six months afterward.
Breastfeeding
Breastfeeding is not recommended with ribavirin-containing treatment; safety of boceprevir alone is unclear.
Interactions
- Strong enzyme-inducing medicines can reduce boceprevir levels and treatment effectiveness.
- Boceprevir can increase levels of some statins, sedatives, and immunosuppressants.
- Avoid rifampin, carbamazepine, phenytoin, and St. John’s wort.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.