About bilvalirudin
Direct thrombin inhibitor anticoagulant
Used for
- Prevents blood clots during coronary angioplasty (PCI).
- Used with aspirin to treat certain adults with acute coronary syndrome undergoing PCI.
Usual adult dose
PCI: intravenous bolus 0.75 mg/kg, then infusion 1.75 mg/kg/hour during the procedure; dosing may vary by indication and kidney function.
Common side effects
- Bleeding
- Low blood pressure
- Nausea
- Back pain
Important warnings
- Can cause serious or fatal bleeding.
- Dose adjustment may be needed with impaired kidney function.
- Not recommended in severe uncontrolled bleeding.
- Anticoagulant effect can increase with other blood thinners.
Pregnancy
Use only when clearly needed; human pregnancy data are limited, and bleeding risks must be considered.
Breastfeeding
It is unknown whether bivalirudin passes into breast milk; breastfeeding data are limited.
Interactions
- Other anticoagulants, including heparin, warfarin, and direct oral anticoagulants, increase bleeding risk.
- Antiplatelet medicines, including aspirin and clopidogrel, increase bleeding risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.