About bempedoic acid
ATP-citrate lyase inhibitor
Used for
- Lowers LDL cholesterol in adults with high cholesterol, alongside diet and other lipid-lowering treatment.
Usual adult dose
180 mg by mouth once daily.
Common side effects
- Muscle spasms
- Back or limb pain
- Raised uric acid or gout
- Raised liver enzymes
Important warnings
- May increase uric acid and trigger gout.
- Can rarely cause tendon injury or rupture.
- Not recommended with simvastatin above 20 mg daily or pravastatin above 40 mg daily.
- Avoid during pregnancy; stop if pregnancy occurs.
Pregnancy
Avoid; it may harm fetal development, and treatment should be stopped if pregnancy occurs.
Breastfeeding
Breastfeeding is not recommended during treatment; discuss alternatives with a healthcare professional.
Interactions
- Simvastatin: increased risk of muscle toxicity, especially above 20 mg daily.
- Pravastatin: increased risk of muscle toxicity, especially above 40 mg daily.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.