About baloxavir marboxil
Antiviral; influenza cap-dependent endonuclease inhibitor
Used for
- Treatment of uncomplicated influenza in people aged five years and older, within 48 hours of symptoms.
- Prevention of influenza after exposure in people aged five years and older.
Usual adult dose
One dose by mouth within 48 hours: 40 mg if weighing under 80 kg; 80 mg if weighing 80 kg or more.
Usual dose in children
One dose by mouth within 48 hours: 40 mg at 20 to under 80 kg; 80 mg at 80 kg or more. For children under 20 kg, dosing is weight-based and requires the appropriate formulation.
Common side effects
- Diarrhea
- Nausea
- Headache
- Bronchitis
Important warnings
- Not a substitute for influenza vaccination.
- Avoid taking with dairy products, calcium-fortified drinks, antacids, or supplements containing polyvalent cations.
- Effectiveness is not established for severe or hospitalized influenza.
- Influenza viruses can develop resistance during treatment.
Pregnancy
Human pregnancy data are limited; use only when potential benefit justifies potential risk.
Breastfeeding
It is unknown whether baloxavir passes into human milk; effects on a nursing infant are unknown.
Interactions
- Calcium, iron, magnesium, selenium, or zinc supplements may reduce absorption.
- Antacids containing polyvalent cations may reduce absorption.
- Dairy products and calcium-fortified beverages may reduce absorption.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.