About aztreonam m
Monobactam antibiotic plus beta-lactamase inhibitor
Used for
- Treats certain serious bacterial infections in adults, including hospital-acquired pneumonia and complicated abdominal or urinary infections.
- Used when bacteria are resistant to other antibiotics, including some infections caused by metallo-beta-lactamase-producing bacteria.
Usual adult dose
Usually 2 g aztreonam plus 0.67 g avibactam intravenously every 6 hours; treatment length depends on infection.
Common side effects
- Anaemia
- Diarrhoea, nausea, or vomiting
- Abnormal liver blood tests
- Infusion-site reactions or rash
Important warnings
- For intravenous use under medical supervision.
- Serious allergic reactions can occur, especially with previous severe beta-lactam allergy.
- Antibiotic-associated severe diarrhoea may occur during or after treatment.
- Dose adjustment may be needed with reduced kidney function.
Pregnancy
Human data are limited. Use during pregnancy only when a clinician considers it necessary.
Breastfeeding
It is unknown whether both medicines pass into breast milk; a clinician should weigh treatment benefits and risks.
Interactions
- Probenecid may increase aztreonam exposure.
- Medicines affecting kidney function may require closer monitoring.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.