About aztreonam
Monobactam antibiotic
Used for
- Treats serious infections caused by susceptible Gram-negative bacteria.
- May be used for urinary, lung, bloodstream, skin, and abdominal infections.
Usual adult dose
Usually 1–2 g intravenously or intramuscularly every 8–12 hours; severe infections may need more frequent dosing, adjusted for kidney function.
Usual dose in children
For children at least 9 months old, usually 30 mg/kg intravenously every 6–8 hours; severe infections may require up to 50 mg/kg per dose. Maximum 2 g per dose.
Common side effects
- Diarrhea, nausea, or vomiting
- Injection-site pain or inflammation
- Rash or itching
- Abnormal liver tests
Important warnings
- Use only for bacterial infections; it does not treat viral illnesses.
- Serious allergic reactions can occur; cross-reactions with other beta-lactam antibiotics are uncommon but possible.
- Dose adjustment may be needed with reduced kidney function.
- Antibiotic-associated severe diarrhea can occur during or after treatment.
Pregnancy
Human pregnancy data are limited. Use when clearly needed after a clinician weighs potential benefits and risks.
Breastfeeding
Aztreonam enters breast milk in small amounts; infant effects are considered unlikely, but monitor for diarrhea or thrush.
Interactions
- Probenecid may increase aztreonam levels.
- Use with other medicines that affect kidney function may increase kidney-related risks.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.