About azacitidine
Antineoplastic pyrimidine nucleoside analogue
Used for
- Myelodysplastic syndromes
- Acute myeloid leukemia in selected patients
- Chronic myelomonocytic leukemia
Usual adult dose
Usually 75 mg/m² injected under the skin or into a vein daily for 7 days, repeated every 28 days.
Common side effects
- Low blood cell counts
- Nausea or vomiting
- Diarrhea or constipation
- Injection-site reactions
Important warnings
- Can cause severe bone marrow suppression and serious infections or bleeding.
- May cause fetal harm; pregnancy should be avoided during treatment.
- Use caution with kidney or liver problems.
- Treatment requires regular blood-count and organ-function monitoring.
Pregnancy
May cause fetal harm. Avoid use during pregnancy; effective contraception is recommended during treatment and for a period afterward.
Breastfeeding
Breastfeeding is not recommended during treatment and for one week after the last dose.
Interactions
- Other medicines that suppress bone marrow may increase blood-count problems.
- Medicines affecting kidney function may increase toxicity risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.