About axitinib
Tyrosine kinase inhibitor
Used for
- Treats advanced kidney cancer (renal cell carcinoma), often with other cancer medicines.
Usual adult dose
Usually 5 mg by mouth twice daily; dose may be adjusted based on response and side effects.
Common side effects
- Diarrhea, nausea, vomiting, or constipation
- High blood pressure
- Tiredness, reduced appetite, or weight loss
- Hand-foot skin reactions
Important warnings
- Can cause severe bleeding, blood clots, or slow wound healing.
- May cause high blood pressure, heart problems, or thyroid problems.
- Risk of liver injury; liver tests are monitored.
- Can harm an unborn baby; effective contraception is important during treatment.
Pregnancy
May harm an unborn baby. Avoid during pregnancy; use effective contraception during treatment and for one week after the last dose.
Breastfeeding
Do not breastfeed during treatment and for two weeks after the last dose.
Interactions
- Strong CYP3A4/5 inhibitors may raise axitinib levels.
- Strong CYP3A4/5 inducers may lower axitinib levels.
- Avoid grapefruit and grapefruit juice.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.