About avanafil
Phosphodiesterase type 5 inhibitor
Used for
- Treats erectile dysfunction in adult men.
Usual adult dose
Usually 100 mg about 15–30 minutes before sexual activity; maximum once daily. A clinician may adjust the dose.
Common side effects
- Headache
- Flushing
- Nasal congestion
- Dizziness
Important warnings
- Sexual stimulation is needed for the medicine to work.
- Never use with nitrate medicines or riociguat; blood pressure may fall dangerously.
- Seek urgent care for an erection lasting over four hours or sudden vision or hearing loss.
- Use caution with heart disease, low blood pressure, or medicines affecting blood pressure.
Pregnancy
Not indicated for use in women; pregnancy safety is not established.
Breastfeeding
Not indicated for use in women; breastfeeding safety is not established.
Interactions
- Nitrates, nitric oxide donors, or riociguat can cause dangerous low blood pressure.
- Strong CYP3A4 inhibitors, including ketoconazole and ritonavir, can greatly increase avanafil levels.
- Alpha-blockers and some blood-pressure medicines may increase dizziness or low blood pressure.
- Other erectile dysfunction medicines should not be combined without medical direction.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.