About avalglucosidase alfa
Enzyme replacement therapy
Used for
- Long-term enzyme replacement for late-onset Pompe disease in adults and children.
Usual adult dose
20 mg/kg by intravenous infusion every two weeks.
Usual dose in children
20 mg/kg by intravenous infusion every two weeks; used in children aged 1 year and older.
Common side effects
- Headache
- Nausea
- Diarrhea
- Infusion-related or allergic reactions
Important warnings
- Serious allergic reactions, including anaphylaxis, can occur.
- Infusion reactions may require slowing or stopping the infusion.
- Some people develop antibodies that may affect treatment or cause reactions.
- Use caution with heart or breathing problems.
Pregnancy
Human pregnancy data are limited; use only when potential benefits justify possible risks.
Breastfeeding
It is unknown whether avalglucosidase alfa enters breast milk; consider treatment benefits and breastfeeding needs.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.