About avalglucosidase
Enzyme replacement therapy
Used for
- Long-term treatment of late-onset Pompe disease in adults and children.
Usual adult dose
20 mg/kg by intravenous infusion every two weeks.
Usual dose in children
20 mg/kg by intravenous infusion every two weeks for children with late-onset Pompe disease.
Common side effects
- Headache
- Nausea or vomiting
- Diarrhea
- Infusion-related reactions, including rash or breathing difficulty
Important warnings
- Infusion reactions can be severe or life-threatening; close monitoring is required.
- Serious allergic reactions, including anaphylaxis, may occur.
- Antibodies may reduce treatment effect or increase reactions.
- Use caution with heart or lung problems and during infusions.
Pregnancy
Limited information; use during pregnancy only when clearly needed after weighing potential benefits and risks.
Breastfeeding
Unknown whether avalglucosidase passes into breast milk; consider treatment benefits and breastfeeding needs.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.