About atracurium besylate
Non-depolarizing neuromuscular blocker
Used for
- Relaxes muscles during general anaesthesia and surgery
- Helps with placement of a breathing tube and mechanical ventilation
Usual adult dose
Given by intravenous injection or infusion by an anaesthesia professional; dose is adjusted to body weight and response.
Usual dose in children
Used in children under specialist anaesthesia care; dose is adjusted to body weight and response.
Common side effects
- Low blood pressure
- Flushing
- Wheezing or bronchospasm
- Slow heart rate
Important warnings
- Causes paralysis, including of breathing muscles; ventilation and monitoring are essential.
- Must be given by trained staff with resuscitation equipment available.
- Can release histamine, occasionally causing severe allergic reactions or low blood pressure.
- Does not cause unconsciousness or pain relief; anaesthesia is also required.
Pregnancy
Use only when clinically necessary; evidence in pregnancy is limited.
Breastfeeding
No adequate information; discuss use with the treating specialist.
Interactions
- Other neuromuscular blockers can intensify or prolong paralysis.
- Some antibiotics, including aminoglycosides, can intensify neuromuscular blockade.
- Certain anaesthetics, such as inhaled agents, can enhance its effects.
- Magnesium salts may increase or prolong muscle relaxation.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.