About asenapine maleate
Atypical antipsychotic
Used for
- Treatment of schizophrenia in adults.
- Treatment of manic or mixed episodes associated with bipolar I disorder in adults.
Usual adult dose
Schizophrenia: 5 mg under the tongue twice daily. Bipolar mania: 5–10 mg twice daily.
Common side effects
- Sleepiness or dizziness
- Restlessness or movement symptoms
- Numbness or tingling in the mouth
- Weight gain
Important warnings
- Can cause severe allergic reactions, including swelling and breathing difficulty.
- May cause low blood pressure, falls, or impaired alertness.
- Can raise blood sugar and cholesterol; monitor metabolic health.
- May cause involuntary movements or a rare, life-threatening fever and muscle reaction.
Pregnancy
Use during pregnancy only when clinically necessary; newborns exposed late in pregnancy may have movement or withdrawal symptoms.
Breastfeeding
Breastfeeding is generally not recommended during treatment because asenapine may affect the infant.
Interactions
- Alcohol and sedating medicines can increase drowsiness.
- Fluvoxamine may increase asenapine levels.
- Medicines that prolong the QT interval may increase heart rhythm risks.
- Some medicines affecting liver enzymes can alter asenapine levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.