About articaine + norepinephrine bitartrate
Local anesthetic with vasoconstrictor
Used for
- Local anesthesia for dental procedures
Usual adult dose
Dental use: typically 1–2 cartridges, injected as needed; dose depends on procedure and product labeling.
Usual dose in children
For children aged 4 years and older: typically 5–6 mg/kg; do not exceed labeled limits.
Common side effects
- Numbness or tingling
- Injection-site pain or swelling
- Dizziness or headache
- Palpitations or increased blood pressure
Important warnings
- For dental injection by trained clinicians only.
- Avoid accidental injection into blood vessels; serious reactions can occur.
- Use caution with heart disease, high blood pressure, or thyroid disorders.
- Excess doses may cause seizures or heart rhythm problems.
Pregnancy
Use only when clinically needed; pregnancy-specific safety data are limited.
Breastfeeding
Small amounts are expected to enter milk; available information suggests low risk.
Interactions
- Other local anesthetics can increase toxic effects.
- Medicines affecting heart rhythm may increase cardiac risks.
- Nonselective beta blockers can intensify norepinephrine-related blood pressure effects.
- Tricyclic antidepressants may intensify vasoconstrictor effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.