About articaine + epinephrine
Local anesthetic with vasoconstrictor
Used for
- Local anesthesia for dental procedures, including infiltration and nerve blocks
Usual adult dose
Dentist-administered; usually 7 mg/kg maximum, not exceeding 500 mg per procedure.
Usual dose in children
Age 4 years and older: usually 5–7 mg/kg; maximum 7 mg/kg per procedure.
Common side effects
- Numbness or tingling
- Pain or swelling at injection site
- Headache or dizziness
- Rapid heartbeat or palpitations
Important warnings
- For dental injection by trained professionals only.
- Avoid accidental injection into a blood vessel; use the lowest effective dose.
- Use caution with heart disease, high blood pressure, or sulfite sensitivity.
- Seek urgent care for seizure, breathing difficulty, or severe allergic reaction.
Pregnancy
Use only when clinically needed; adequate human pregnancy data are limited.
Breastfeeding
Articaine and epinephrine enter breast milk in small amounts; brief dental use is generally considered compatible.
Interactions
- Nonselective beta blockers may cause severe high blood pressure and slow heartbeat.
- Tricyclic antidepressants and some other medicines may intensify epinephrine effects.
- Other local anesthetics can increase systemic toxicity.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.