About apalutamide
Androgen receptor inhibitor
Used for
- Non-metastatic castration-resistant prostate cancer
- Metastatic castration-sensitive prostate cancer
Usual adult dose
240 mg by mouth once daily, with ongoing medical or surgical castration.
Common side effects
- Fatigue
- Rash
- Falls and fractures
- High blood pressure
Important warnings
- Can cause seizures; stop treatment if one occurs.
- May cause serious falls or fractures.
- Can harm an unborn baby; use effective contraception during treatment and for three months afterward.
- Monitor for heart disease and thyroid problems.
Pregnancy
Not for use during pregnancy; may harm a developing baby.
Breastfeeding
Not indicated for breastfeeding; human milk exposure is unknown.
Interactions
- Can reduce the effects of many medicines, including warfarin and hormonal contraceptives.
- Strong enzyme-inducing medicines, such as rifampin, can lower apalutamide levels.
- Apalutamide can reduce levels of many medicines; medication review is important.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.