About antimony pentavalent
Pentavalent antimonial antiparasitic
Used for
- Treatment of visceral leishmaniasis
- Treatment of cutaneous leishmaniasis
- Treatment of mucosal leishmaniasis
Usual adult dose
Usually 20 mg antimony/kg injected once daily for 20–28 days; regimen depends on disease and region.
Usual dose in children
Usually 20 mg antimony/kg injected once daily for 20–28 days; regimen depends on disease and region.
Common side effects
- Nausea, vomiting, abdominal pain
- Muscle or joint pain
- Injection-site pain
- Abnormal heart rhythm or pancreatitis
Important warnings
- Requires specialist supervision and monitoring of heart rhythm, blood counts, liver, kidneys, and pancreas.
- Can cause serious heart rhythm problems, pancreatitis, and liver or kidney injury.
- Avoid or use cautiously with heart, liver, or kidney disease.
- Treatment choice and effectiveness vary with parasite species and regional resistance.
Pregnancy
Safety is uncertain; use only when specialist assessment concludes treatment benefits outweigh potential fetal risks.
Breastfeeding
Safety information is limited; specialist advice is needed before use.
Interactions
- Medicines that affect heart rhythm may increase cardiac risk.
- Other medicines toxic to the pancreas, liver, or kidneys may increase organ injury risks.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.