About antilymphocyte immunoglobulin
Rabbit polyclonal immunosuppressant
Used for
- Prevention and treatment of acute organ-transplant rejection
- Treatment of aplastic anaemia
Usual adult dose
Varies by indication and protocol; commonly 2–5 mg/kg intravenously daily for several days.
Usual dose in children
Specialist-determined, usually weight-based intravenous dosing; protocols vary by indication.
Common side effects
- Fever and chills
- Low blood cell counts
- Infections
- Allergic or infusion reactions
Important warnings
- Given intravenously in hospital under specialist supervision.
- Can cause severe allergic reactions, including anaphylaxis.
- Raises risk of serious infections and some cancers.
- Blood counts and infusion reactions require monitoring.
Pregnancy
Use only when clearly needed; pregnancy data are limited, and maternal immunosuppression may affect the fetus.
Breastfeeding
Breastfeeding safety is uncertain; specialist assessment is needed.
Interactions
- Other immunosuppressants can increase infection risk.
- Live vaccines may be unsafe during treatment.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.