About anagrelide hydrochloride
Platelet-lowering medicine (thrombocytosis treatment)
Used for
- Reduces high platelet counts in essential thrombocythemia.
Usual adult dose
Usually started at 0.5 mg four times daily or 1 mg twice daily; adjusted gradually to response.
Common side effects
- Headache
- Fast heartbeat or palpitations
- Diarrhea
- Fluid retention or swelling
Important warnings
- Can cause serious heart problems; monitoring is needed.
- May increase bleeding risk, especially with other medicines affecting clotting.
- Monitor blood counts and liver function during treatment.
- Do not stop suddenly without medical supervision; platelet counts may rise.
Pregnancy
May harm an unborn baby; generally avoid during pregnancy unless clearly necessary.
Breastfeeding
Breastfeeding is not recommended during treatment.
Interactions
- Aspirin and other medicines that increase bleeding risk
- Other medicines that prolong the QT interval
- CYP1A2 inhibitors, such as fluvoxamine or ciprofloxacin
- CYP1A2 inducers, such as omeprazole
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.