About amylase + lipase + protease
Pancreatic enzyme replacement therapy
Used for
- Treats digestive problems caused by insufficient pancreatic enzymes, including cystic fibrosis and chronic pancreatitis.
- Helps digest fats, proteins, and carbohydrates.
Usual adult dose
Individualized with meals and snacks; commonly 25,000–80,000 lipase units per meal, adjusted to response.
Usual dose in children
Individualized by weight and meals; commonly 500–2,500 lipase units/kg per meal, with age-specific limits.
Common side effects
- Abdominal pain or bloating
- Nausea or vomiting
- Constipation or diarrhea
- Anal irritation
Important warnings
- Swallow capsules whole; do not crush or chew.
- Take with meals or snacks; follow product instructions if opening capsules.
- High doses may rarely cause serious bowel narrowing, especially in cystic fibrosis.
- Some products contain pork-derived enzymes; allergy may be relevant.
Pregnancy
Human data are limited; enzymes are poorly absorbed, and use may be considered when needed under clinician guidance.
Breastfeeding
Expected exposure through breast milk is low because enzymes are poorly absorbed; use when needed under clinician guidance.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.