About ampicillin + sulbactam
Penicillin antibiotic with beta-lactamase inhibitor
Used for
- Treats susceptible bacterial infections, including skin, abdominal, and gynecological infections.
Usual adult dose
Commonly 1.5–3 g intravenously or intramuscularly every 6 hours; dose depends on infection and kidney function.
Usual dose in children
Children aged 1 year and older: commonly 300 mg/kg/day total, divided every 6 hours; maximum 12 g daily.
Common side effects
- Diarrhea, nausea, or vomiting
- Rash or itching
- Injection-site pain
- Serious allergic reaction
Important warnings
- Avoid with serious allergy to penicillins or other beta-lactam antibiotics.
- Kidney impairment may require dose adjustment.
- Seek urgent care for breathing difficulty, severe rash, or persistent watery or bloody diarrhea.
- Use only for infections caused by susceptible bacteria.
Pregnancy
Generally considered usable when clinically needed; human pregnancy data are limited.
Breastfeeding
Usually compatible; small amounts may enter breast milk and cause infant diarrhea or thrush.
Interactions
- Probenecid can increase antibiotic levels.
- May reduce the effectiveness of oral live typhoid vaccine.
- May affect some urine glucose tests.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.