About amphetamine + dextroamphetamine
Central nervous system stimulant
Used for
- Attention-deficit/hyperactivity disorder (ADHD)
- Narcolepsy
Usual adult dose
ADHD: usually 5 mg once or twice daily initially; adjust gradually. Narcolepsy: usually 5–60 mg daily in divided doses.
Usual dose in children
ADHD, ages 3–5: usually 2.5 mg daily initially. Ages 6 and older: 5 mg once or twice daily initially; adjust gradually. Not generally used for narcolepsy in children.
Common side effects
- Reduced appetite and weight loss
- Insomnia
- Dry mouth
- Increased heart rate or blood pressure
Important warnings
- Can cause misuse, dependence, or overdose; store securely.
- May worsen serious heart problems or psychiatric symptoms.
- Avoid with monoamine oxidase inhibitors or within 14 days of stopping them.
- Growth, blood pressure, and heart rate may need monitoring.
Pregnancy
May harm fetal growth; use during pregnancy requires careful benefit-risk assessment.
Breastfeeding
Not recommended during breastfeeding; amphetamine enters breast milk and may affect the infant.
Interactions
- Monoamine oxidase inhibitors can cause dangerously high blood pressure.
- Other stimulants and some antidepressants may increase side effects.
- Alkalinizing agents may increase amphetamine levels; acidifying agents may reduce them.
- May reduce the effectiveness of some blood pressure medicines.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.