About amoxcillin as trihydrate
Penicillin antibiotic with beta-lactamase inhibitor
Used for
- Treats certain bacterial ear, sinus, lung, skin, and urinary infections.
Usual adult dose
Usual adult regimens vary by infection; commonly 500 mg/125 mg every eight hours or 875 mg/125 mg every twelve hours.
Usual dose in children
For children aged three months or older, dosing is based on amoxicillin: commonly 25–45 mg/kg/day divided every twelve hours; higher doses may be prescribed for some infections.
Common side effects
- Diarrhea, nausea, vomiting, or rash.
- Rarely, severe allergic reactions or liver problems.
Important warnings
- Avoid with serious allergy to penicillins or related antibiotics.
- Seek urgent care for breathing difficulty, facial swelling, or severe skin reactions.
- Antibiotics do not treat viral infections.
- Dose adjustments may be needed with kidney disease.
Pregnancy
Generally considered usable during pregnancy when prescribed; evidence has not shown a clear increase in birth defects.
Breastfeeding
Usually compatible with breastfeeding; infant diarrhea, rash, or thrush may occur.
Interactions
- Warfarin and other anticoagulants: bleeding tests may need monitoring.
- Allopurinol: increased chance of skin rash.
- Probenecid: can increase amoxicillin levels.
- Methotrexate: may increase methotrexate exposure.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.