About amobarbital sodium
Barbiturate sedative-hypnotic
Used for
- Short-term sedation or treatment of severe insomnia, where available.
- Pre-anesthetic sedation.
- Specialist-supervised diagnostic interviews in selected settings.
Usual adult dose
Dose varies by purpose and route; injectable dosing must be determined and administered by a clinician.
Common side effects
- Drowsiness, dizziness, confusion, and poor coordination.
- Low blood pressure and slowed breathing.
- Nausea or vomiting.
- Dependence and withdrawal with repeated use.
Important warnings
- Can cause life-threatening respiratory depression, coma, or death, especially with overdose.
- Avoid alcohol and other sedatives unless specifically directed by a clinician.
- Risk of dependence; abrupt stopping after regular use can cause severe withdrawal.
- Use requires close medical supervision; availability and approved uses vary by country.
Pregnancy
May harm the fetus, particularly with prolonged use or near delivery; use only when a clinician considers it necessary.
Breastfeeding
May enter breast milk and cause infant sedation or breathing problems; use requires clinician guidance.
Interactions
- Opioids, alcohol, benzodiazepines, and other sedatives increase breathing and sedation risks.
- Can reduce the effects of hormonal contraceptives and many other medicines.
- Valproate may increase amobarbital effects.
- Other medicines affecting liver enzymes may alter its levels or effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.