About amlodipine besylate + valsartan + hydrochlorothiazide
Calcium channel blocker, ARB, thiazide diuretic
Used for
- Treats high blood pressure when combination therapy is needed.
Usual adult dose
Usually one tablet once daily; doses are individualized and adjusted by a clinician.
Common side effects
- Dizziness or lightheadedness
- Swelling of ankles or feet
- Headache
- Low blood pressure or changes in kidney function
Important warnings
- Can cause low blood pressure, dehydration, or electrolyte imbalances.
- May impair kidney function; monitoring may be needed.
- Avoid during pregnancy because valsartan can harm or kill the developing baby.
- Use caution with kidney or liver disease, gout, or sulfonamide allergy.
Pregnancy
Not recommended; valsartan can cause serious fetal injury or death, especially later in pregnancy.
Breastfeeding
Information is limited; this combination is generally not preferred while breastfeeding, particularly for newborns or premature infants.
Interactions
- NSAIDs, such as ibuprofen, may worsen kidney function or reduce blood-pressure effects.
- Lithium levels may rise and cause toxicity.
- Potassium supplements or potassium-sparing medicines may raise potassium levels.
- Other blood-pressure medicines or alcohol may increase dizziness or low blood pressure.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.