About amiodaron e
Class III antiarrhythmic
Used for
- Treatment of severe, potentially life-threatening heart rhythm disturbances, usually when other treatments fail.
Usual adult dose
Usually 5 mg/kg by intravenous infusion over 20 minutes to 2 hours; further doses depend on response and monitoring.
Usual dose in children
Specialist-directed dosing by weight; safety and dosing vary with age and heart rhythm condition.
Common side effects
- Low blood pressure
- Slow heart rate or heart block
- Nausea
- Infusion-site inflammation
Important warnings
- Given with continuous heart and blood pressure monitoring.
- Can cause serious rhythm disturbances, especially with rapid administration.
- May affect the thyroid, liver, lungs, eyes, and skin.
- Injection may contain benzyl alcohol; check product information for newborns.
Pregnancy
Use only when clearly necessary; amiodarone may affect the fetal thyroid.
Breastfeeding
Generally avoid breastfeeding during treatment because amiodarone enters milk and may affect the infant’s thyroid.
Interactions
- May increase digoxin and warfarin effects.
- Other medicines that prolong the QT interval increase rhythm risks.
- Combining with beta-blockers or some calcium-channel blockers may excessively slow the heart.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.