About amantadine sulfate
Antiviral and antiparkinsonian medicine
Used for
- Parkinson’s disease and medicine-induced movement symptoms
- Influenza A treatment or prevention; use varies by country and resistance patterns
Usual adult dose
Parkinson’s disease: often 100 mg once daily initially, increasing to 100 mg twice daily if needed. Doses may be lower in older adults or kidney impairment.
Common side effects
- Nausea, dry mouth, constipation, or blurred vision
- Dizziness, sleep problems, or confusion
- Swollen ankles or mottled skin
- Rarely, hallucinations or seizures
Important warnings
- Kidney impairment requires dose adjustment; accumulation can cause serious toxicity.
- Do not stop suddenly when used for Parkinson’s disease; symptoms may worsen.
- Use caution with glaucoma, heart problems, seizures, or mental health conditions.
- Influenza use depends on local guidance because resistance is widespread.
Pregnancy
Use only when clearly needed after clinician assessment; human pregnancy information is limited.
Breastfeeding
Amantadine enters breast milk and may reduce milk supply; use requires clinician assessment.
Interactions
- Anticholinergic medicines can worsen confusion, dry mouth, or urinary problems.
- Other medicines affecting the nervous system may increase dizziness or confusion.
- Urine-alkalinizing medicines can increase amantadine levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.