About amantadine hydrochloride
Antiviral and antiparkinsonian medicine
Used for
- Treatment of Parkinson’s disease symptoms
- Treatment or prevention of influenza A, where recommended
Usual adult dose
Parkinson’s disease: usually 100 mg by mouth once or twice daily; IV use requires specialist dosing.
Common side effects
- Nausea, dizziness, or dry mouth
- Insomnia or confusion
- Swelling of legs
- Low blood pressure when standing
Important warnings
- Dose reduction may be needed with kidney problems.
- Can worsen confusion, hallucinations, or other mental health symptoms.
- Use caution with seizures, heart problems, or urinary retention.
- IV administration requires healthcare supervision; formulation-specific guidance is essential.
Pregnancy
Limited evidence; use only when clearly needed after weighing potential risks.
Breastfeeding
May reduce milk supply and passes into breast milk; use requires clinical assessment.
Interactions
- Other medicines affecting the brain may increase confusion or drowsiness.
- Anticholinergic medicines can worsen dry mouth, constipation, or urinary retention.
- Some diuretics can raise amantadine levels.
- Live influenza vaccines may be less effective during treatment.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.