About aflibercept
Vascular endothelial growth factor inhibitor
Used for
- Treats wet age-related macular degeneration
- Treats diabetic macular edema and diabetic retinopathy
- Treats macular edema after retinal vein blockage
- Treats certain forms of myopic choroidal neovascularization
Usual adult dose
Usually 2 mg injected into the eye every 4 weeks initially; intervals may later be extended depending on condition and response.
Common side effects
- Eye pain, redness, irritation, or floaters
- Increased pressure inside the eye
- Cataract or retinal detachment
- Rarely, blood clots or serious eye infection
Important warnings
- Administered by an eye specialist as an injection into the eye
- Seek urgent care for sudden vision changes, severe eye pain, or worsening redness
- May increase risk of arterial blood clots
- Do not use with an active eye infection or significant eye inflammation
Pregnancy
Avoid during pregnancy when possible; potential fetal risk is uncertain. Effective contraception is advised during treatment and for at least three months afterward.
Breastfeeding
Effects on a breastfed infant are unknown; discuss treatment and breastfeeding with a clinician.
Interactions
- Few established medicine interactions; tell the eye specialist about all medicines and supplements
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.