About epinephrine
Adrenergic agonist; emergency medicine
Used for
- Severe allergic reactions (anaphylaxis)
- Cardiac arrest, using a different concentration and route
- Severe asthma attacks in selected settings
Usual adult dose
Anaphylaxis: 0.3–0.5 mg intramuscularly; repeat every 5–15 minutes if needed.
Usual dose in children
Anaphylaxis: 0.01 mg/kg intramuscularly (maximum 0.5 mg); repeat every 5–15 minutes if needed.
Common side effects
- Fast or pounding heartbeat
- Shaking, anxiety, or headache
- Paleness, sweating, or dizziness
- Nausea or vomiting
Important warnings
- This concentrated solution is for intramuscular or subcutaneous use, not intravenous injection.
- Intravenous adrenaline requires dilution and close monitoring by trained clinicians.
- May worsen heart rhythm problems, high blood pressure, or chest pain.
- Anaphylaxis needs urgent emergency medical care, even after symptoms improve.
Pregnancy
For anaphylaxis, adrenaline should not be withheld; untreated severe allergy can endanger both pregnant person and fetus.
Breastfeeding
Emergency use for anaphylaxis is generally compatible with breastfeeding; treatment should not be delayed.
Interactions
- Some beta-blockers may reduce its effects or cause an unusual blood-pressure response.
- Tricyclic antidepressants and monoamine oxidase inhibitors may increase cardiovascular effects.
- Other stimulants or decongestants can increase heart rate and blood pressure.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.