About ademetionine
Amino acid derivative; methyl donor
Used for
- Used in some countries for cholestatic liver disease and depressive symptoms.
- Evidence and approved uses vary by country.
Usual adult dose
Common oral regimens are 800–1600 mg daily; dosing depends on the condition and local product information.
Common side effects
- Nausea, diarrhea, abdominal discomfort
- Headache, dizziness, anxiety, or insomnia
Important warnings
- May trigger mania in people with bipolar disorder.
- Use caution with liver disease, kidney impairment, or older age.
- Seek medical assessment for worsening jaundice or other severe symptoms.
Pregnancy
Safety is not well established; use during pregnancy only when a clinician considers it necessary.
Breastfeeding
Safety information is limited; use only with clinician guidance.
Interactions
- Serotonergic medicines, including antidepressants, may increase serotonin-related adverse effects.
- Use caution with levodopa; ademetionine may affect its effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.