About adefovir dipivoxil
Antiviral nucleotide analogue
Used for
- Treats chronic hepatitis B in adults and children aged 12 years or older.
Usual adult dose
10 mg by mouth once daily for chronic hepatitis B.
Usual dose in children
For ages 12–17: 10 mg by mouth once daily. Not established for younger children.
Common side effects
- Weakness or headache
- Stomach pain, nausea, or diarrhea
- Kidney problems
- Rare severe lactic acidosis or liver enlargement
Important warnings
- Can harm the kidneys; kidney function monitoring is important.
- Hepatitis may worsen after stopping treatment; medical follow-up is needed.
- Rarely causes lactic acidosis or severe liver enlargement.
- Does not prevent hepatitis B transmission.
Pregnancy
Human pregnancy information is limited; discuss treatment decisions with a clinician. Untreated hepatitis B also carries risks.
Breastfeeding
It is not known whether adefovir passes into breast milk; discuss breastfeeding with a clinician.
Interactions
- Tenofovir or other medicines that can harm the kidneys may increase kidney risk.
- Medicines affecting kidney function may change adefovir exposure.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.