About abiraterone acetate usp
Androgen biosynthesis inhibitor
Used for
- Treats prostate cancer that has spread or is at high risk of spreading, with other medicines.
Usual adult dose
1,000 mg once daily with prednisone or prednisolone; take on an empty stomach.
Common side effects
- High blood pressure
- Low blood potassium
- Fluid retention
- Liver problems
Important warnings
- Check liver function, blood pressure, and potassium regularly.
- Do not use in pregnancy; people who could become pregnant should avoid handling broken tablets.
- Take with prescribed prednisone or prednisolone; stopping steroids suddenly can be dangerous.
- Avoid food around dosing because it can greatly increase absorption.
Pregnancy
Can harm a developing fetus. Use effective contraception during treatment and for one week after the last dose.
Breastfeeding
Breastfeeding is not recommended during treatment.
Interactions
- Strong CYP3A4 inducers, such as rifampin, may reduce abiraterone levels.
- May increase levels of CYP2D6 substrates, including some heart medicines.
- May affect medicines processed by CYP2C8, including pioglitazone and repaglinide.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.