About abirateron e acetate
Androgen biosynthesis inhibitor
Used for
- Treats advanced prostate cancer with other medicines, including a corticosteroid.
Usual adult dose
Usually 1,000 mg by mouth once daily, with prednisone or prednisolone; take on an empty stomach.
Common side effects
- High blood pressure
- Low potassium or fluid retention
- Liver problems
- Joint pain or fatigue
Important warnings
- Monitor liver tests, blood pressure, and potassium.
- Can cause serious liver injury and adrenal problems.
- Do not use during pregnancy; handling damaged tablets may expose others.
- Take on an empty stomach; food can greatly increase absorption.
Pregnancy
Not for use in pregnancy. It may harm a developing fetus.
Breastfeeding
Not for use while breastfeeding; safety is not established.
Interactions
- Strong CYP3A4 inducers can lower abiraterone levels.
- May alter levels of medicines metabolized by CYP2D6 or CYP2C8.
- Spironolactone may interfere with treatment.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.