About methyltetrahydrofolate
Active folate (vitamin B9)
Used for
- Helps prevent or treat folate deficiency
- Supports pregnancy neural-tube-defect prevention as part of recommended folate intake
Usual adult dose
Usually 400 mcg once daily for supplementation; deficiency treatment doses vary by cause and clinician guidance.
Usual dose in children
Not routinely used as a standalone medicine in children; dosing depends on age and need.
Common side effects
- Nausea or stomach discomfort
- Bloating
- Headache
- Rare allergic reactions
Important warnings
- High folate intake can mask vitamin B12 deficiency and allow nerve damage to progress.
- Folate deficiency may have causes requiring medical evaluation.
- Dose needs may differ with certain conditions or medicines.
Pregnancy
Folate is important before and during early pregnancy. Recommended amounts and the preferred form may depend on individual risk and local guidance.
Breastfeeding
Folate is normally compatible with breastfeeding; requirements may be higher than for non-lactating adults.
Interactions
- Methotrexate and some cancer treatments may interact with folate.
- Some seizure medicines, including phenytoin, can affect folate levels.
- Sulfasalazine can reduce folate absorption.
- Trimethoprim may interact with folate metabolism.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.