About lamiv udine
Nucleoside reverse transcriptase inhibitor
Used for
- Treatment of HIV infection with other antiretroviral medicines
- Treatment of chronic hepatitis B
Usual adult dose
HIV: 150 mg twice daily or 300 mg once daily with other medicines. Hepatitis B: 100 mg once daily.
Usual dose in children
HIV: usually 4 mg/kg twice daily, maximum 150 mg per dose; dosing depends on age and weight. Hepatitis B dosing is specialist-led.
Common side effects
- Headache
- Nausea or diarrhea
- Tiredness
- Rarely, lactic acidosis or liver enlargement
Important warnings
- HIV treatment requires combination medicines; resistance can develop if used alone.
- Do not stop suddenly when treating hepatitis B; liver inflammation may worsen.
- Dose adjustment may be needed with reduced kidney function.
- Seek urgent care for severe weakness, breathing difficulty, or persistent abdominal symptoms.
Pregnancy
Generally considered suitable during pregnancy when needed for HIV treatment; specialist monitoring is important.
Breastfeeding
HIV can pass through breast milk; recommendations depend on local guidance and individual circumstances.
Interactions
- Trimethoprim can increase lamivudine levels.
- Avoid combining with emtricitabine or other medicines containing lamivudine.
- Sorbitol-containing medicines may reduce lamivudine absorption.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.